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A Possible Conserved Role for SR Protein Kinases in the Regulation of Cell Death (thesis)
Apoptosis, programmed cell death, is a process that mammalian cells frequently undergo to suppress tumors and regulate cell growth. It is unclear whether or not apoptosis is conserved across both multicellular and unicellular ...
Microarray Analysis of Nonfunctional Ribosomal RNA Decay in Saccharomyces cerevisiae (thesis)
Nonfunctional ribosomal RNA decay (NRD) is a eukaryotic degradation pathway that targets and eliminates structurally intact but functionally defective ribosomal RNAs (rRNAs). Two separate NRD pathways for 18S and 25S rRNA ...
An Investigation of Intersubunit Bridges Important for Ribosome Stability in Saccharomyces Cerevisiae
The ribosome, a large ribonucleoprotein complex responsible for protein
biosynthesis, is composed of two unequal subunits that must correctly associate for
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proper function. X-ray crystallographic and cryo-EM studies have ...